Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report
نویسندگان
چکیده
A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection. Although acrocyanosis is commonly associated with cold agglutinin disease, gangrene is a rare complication. Management of secondary cold agglutinin disease is mainly supportive.
منابع مشابه
Epstein-Barr Virus Myocarditis Presenting as Acute Abdomen in a Child: a Case Report
Introduction Epstein-Barr virus (EBV) infection can present with a variety of manifestation. Case Report Here we present a case of a 7 year- old immunocompetent girl who came with acute abdominal pain , had echocardiographic evidence of myocardial dysfunction and finally was diagnosed as a case of serologically proven acute EBV infection. Conclusion...
متن کاملAutoimmune haemolytic anaemia associated with epstein barr virus infection as a severe late complication after kidney transplantation and successful treatment with rituximab: case report
BACKGROUND Autoimmune haemolytic anaemia (AIHA) is a rare complication following kidney transplantation and usually occurs early in its course. It is characterised by autoantibodies or alloantibodies directed against red blood cells (RBCs). CASE PRESENTATION We describe a 44 year old woman who presented 5 years after kidney transplantation with profound transfusion dependent warm AIHA. Invest...
متن کاملHuman parvovirus B 19 and Epstein-Barr virus co-infection in a child with hereditary spherocytosis.
BACKGROUND In patients with chronic congenital haemolytic disorders, human Parvovirus B19 (HPV B19) is frequently involved in pure red-cell aplastic crises. Furthermore, it may inhibit three-lineage haematopoiesis in the bone marrow, causing severe pancytopenia. In such patients, Epstein Barr virus (EBV) infection also seems to share the same mechanism as HPV B19 in inducing bone marrow aplasia...
متن کاملAcute Epstein-Barr virus infection in two elderly individuals.
Most individuals acquire Epstein-Barr virus (EBV) infection in young age. Because of uncommon presentation and misdiagnosis, clinical manifestations are less well described in older age. We present two cases of elderly patients with predominant symptoms attributed to cold agglutinin haemolytic anaemia due to acute EBV infection without fever, lymphadenopathy, pharyngitis or splenomegaly. We con...
متن کاملLymphoma infectious mononucleosis by Epstein-Barr virus: A case report
Background: Epstein-Bar virus (EBV) causes infectious mononucleosis in more than 90% of children. Rarely, mononucleosis may lead to malignancy. The aim the current study was to introduce a child with mononucleosis and persistent adenopathy. Case report: A 4-year-old male patient presented with complaints of fever, shortness of breath and sore throat. He was treated with antibiotics and prednis...
متن کامل